* The hybrid battery may fail. This is the most common problem with the 2006 Highlander Hybrid. The hybrid battery is responsible for providing power to the electric motor, which helps the gasoline engine to power the vehicle. If the hybrid battery fails, the vehicle will not be able to run on electric power and the fuel economy will be significantly reduced.
* The inverter may fail. The inverter is responsible for converting the DC power from the hybrid battery into AC power that can be used by the electric motor. If the inverter fails, the vehicle will not be able to run on electric power and the fuel economy will be significantly reduced.
* The electric motor may fail. The electric motor is responsible for providing power to the wheels of the vehicle. If the electric motor fails, the vehicle will not be able to move.
* The gasoline engine may fail. The gasoline engine is responsible for providing power to the generator, which charges the hybrid battery. If the gasoline engine fails, the vehicle will not be able to run on electric power and the fuel economy will be significantly reduced.
If you are experiencing any of these problems with your 2006 Highlander Hybrid, it is important to take it to a qualified mechanic for diagnosis and repair.